A STAGE-STRUCTURED SI ECO-EPIDEMIOLOGICAL MODEL WITH TIME DELAY AND IMPULSIVE CONTROLLING*

This paper formulates a robust stage-structured SI eco-epidemiological model with periodic constant pulse releasing of infectious pests with pathogens. The authors show that the conditions for global attractivity of the ＇pest-eradication＇ periodic solution and permanence of the system depend on time delay, hence, the authors call it ＂profitless＂. Further, the authors present a pest management strategy in which the pest population is kept under the economic threshold level （ETL） when the pest population is uniformly persistent. By numerical analysis, the authors also show that constant maturation time delay for the susceptible pests and pulse releasing of the infectious pests can bring obvious effects on the dynamics of system.     

应用型高技能数控人才实训模式的研究——以井冈山大学工学院为例

本文介绍了应用型高技能数控人才的培养目标,从加大设备投入、安装通用软件、保证学生实践时间、建立一支高水平师资队伍、加强校企合作这些方面着手,建立了一套较为完善的实训模式,以增强学生的编程、操作、软件应用等方面的能力。     

适度裁减PM3提升中小规模低成熟度组织的管理水平

理论发展图谱显示成熟度模型依次跨越了制造业、软件业、项目主导型组织，理论界近些年广泛开展了项目管理成熟度模型（PM^3）的研究．充分考虑处于PM^3一、二级区间组织（低成熟度组织）的特点，进而结合PM^3相对严谨的结构发现：低成熟度组织需要适度裁减PM^3，进而论证模型裁减的具体实施方式以及有效运行的基本条件．     

辨识智能作动器中迟滞非线性的两种方法

智能化是当今世界的发展趋势。智能材料结构作为研究热点之一,应用于航空、航天、生物及医药等诸多领域。智能作动器与智能传感器是智能材料结构的两个主要研究方向。迟滞现象是存在于大量智能材料中的非线性现象,对整个控制系统可能带来不良影响,如稳定性的恶化甚至丧失等。Preisach模型常用于智能材料中针对迟滞现象的建模。基于一阶滞回曲线获得智能作动器的输入输出数据,从理论上研究了经典Preisach模型两种工程上易实现的辨识方法,并应用到一种真实的智能作动器——WIDS-IA压电型作动器,仿真与实验结果表明,两种辨识方法均有效,且误差在同一数量级。为广泛存在迟滞非线性的智能作动器建模提供了理论依据,并具有工程实用价值。     

A NEW DESCRIPA NEW DESCRIPTOR OF AMINO ACIDS BASED ON THE THREEDIMENSIONAL VECTOR OF ATOMIC INTERACTION FIELD

QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP (QSAR) IS A VERY IMPORTANT TOPIC FOR MANY SCIENTIFIC FIELDS AND CAN BE TERMED AS QUANTITATIVE SEQUENCE ACTIVITY MODELS(QSAM)[1] WHEN REFERRED TO THE RESEARCH ON RELATION- SHIPS BETWEEN STRUCTURES AND ACTIVITIES OF BIOLOGICAL MOLECULES, SUCH AS PROTEINS, AND NUCLEIC ACIDS. HOW- EVER, IT IS VERY DIFFICULT TO ESTABLISH A QSAM MODEL,…     

水雷对舰船的毁伤概率计算模型及仿真

水雷障碍的作战效能研究是目前研究的重点.基于具有机动能力的水雷的特点,综合考虑了水雷障碍中水雷的布放成功率、命中概率、水雷的可靠度和动作概率等主要因素对目标舰船毁伤概率的影响,提出了目标舰船航线的选择服从均匀分布时和目标舰船航向服从正态分布时的目标舰船遭遇水雷概率计算模型,建立了基于具有机动能力水雷对目标舰船的毁伤概率模型,并进行了仿真验证,具有较高的实用性.     

基于隐式梯度模型的混凝土损伤的数值模拟

分析了局部损伤模型在进行混凝土应变软化模拟时存在的问题:网络依赖性和零能量损耗问题;分别应用隐式梯度模型和局部模型对混凝土应变软化进行了模拟。计算表明该隐式梯度模型可较好避免有限元在应变软化模拟时的网络依赖性,预测出的荷载-位移响应与实际情况吻合较好。     

Therapeutic applications of bone marrow-derived stem cells in liver transplantation for end-stage liver diseases

Today, liver transplantation (LT) is the only established treatment for end-stage liver diseases. The de- velopment of LT, including OLT, cadaveric LT, split LT, living donor LT (LDLT), brings hopes to patients with these diseases. However, increasing donor shortage, rejection and life-long immunosuppression with its side effects are the major limitations of this therapy strategy. Bone marrow-derived stem cells (BMDSCs) are capable of differentiating into hepatocyte-like cells and contribute to liver injury repair. The microenvironment of liver injury caused by rejection, ischemia/reperfusion, loss of liver mass, recurrence of HCV and "small-for-size syndrome" after LT can attract a variety of bone marrow-derived stem cell population to the peripheral circulation and then migration to the injury liver to promote the hepatic function restoration. Additionally, BMDSCs can also take part in the functional regeneration of living donor liver after LDLT. This participation in liver regeneration may be associated to the interac- tion between SDF-1and its receptor CXCR4, involving HGF, IL-8, MMP9, and VEGF/VEGFR-2. BMDSC with its bio-characteristics could maintain the allograft tolerance from different angles and in different ways. In conclusion, BMDSCs transplantation, as a new assistant therapeutic method for LT, will ex- pand the space of LT, and provide more survival opportunities for the patients suffering liver diseases in the future.     

磨料射流切割金属套管机理及计算公式

研究和分析了磨料射流切割机理，由于实际工作中固体颗粒做占比例较小，把磨料两相射流假定为稀疏固液两相流，将固体颗粒假定为伪流体，其运动速度与流体运动速度相同。根据弹性力学的固体接触理论，建立了相应的数学模型，得出了磨料颗粒与材料相接触时的最大接触剪应力公式，从而计算出切割套管所需要的最大剪应力，最后通过实例计算，其结果与现场试验结果相吻合，为该技术不断发展及工艺参数选择提供了理论支撑。     

基于模型的飞行控制系统一体化设计技术研究

飞行控制系统设计是一项复杂的系统工程,涉及众多的专业。为了提高系统开发效率,采用MATLAB软件构建了统一的设计平台,使得各专业能够借助平台开展相关设计工作。飞行控制系统一体化设计思路来源于基于模型的设计思想。采用基于模型的设计流程,能够快速完成设计迭代,缩短产品研制周期。作者从飞行控制系统设计的角度,对采用MATLAB软件构建的一体化设计平台及涉及的相关专业技术进行了研究,供广大工程设计人员借鉴。